Polynucleotides
Polynucleotides are regenerative skin treatments designed to support healthier-looking skin by improving hydration, texture, elasticity and the appearance of fine lines. They are particularly popular for delicate areas such as the under-eyes, where the skin can become thin, crepey or tired-looking.
Ameela® polynucleotides are used to support skin regeneration and improve hydration, texture, elasticity and the appearance of fine lines, with treatment tailored to your individual skin concerns.


How polynucleotides work
Polynucleotides are biological molecules that signal your skin cells to begin a deep repair process. By stimulating fibroblasts, they trigger the natural production of collagen and elastin, replenishing the skin's structure from within. This cellular stimulation goes beyond surface hydration, actively regenerating damaged tissue and restoring youthful elasticity and resilience.
Ameela Polynucleotides
Ameela Polynucleotides is a highly effective, bio-stimulating treatment designed to repair skin at a cellular level, targeting specific concerns where traditional fillers may not be suitable.

Under-Eye Rejuvenation
Designed for delicate under-eye skin where improving skin quality is the priority without adding significant volume.

Face & Neck Laxity
Stimulates fibroblast activity to improve skin tightening and elasticity across the mid-face, jawline, and neck.

Scar & Texture Repair
Improves tissue repair mechanisms to reduce the appearance of acne scarring and uneven skin texture.
Areas We Treat

Facial Rejuvenation
- Under-eye area (dark circles)
- Periorbital lines (crow's feet)
- Cheeks and mid-face
- Perioral lines (smoker's lines)
- General facial skin laxity

Neck & Body Areas
- Neck lines and laxity
- Décolletage rejuvenation
- Stretch marks and scarring
What to Expect
Your Ameela polynucleotide treatment is a simple, medical-led procedure designed for comfort and effective skin regeneration.
01
Preparation
The treatment area is thoroughly cleansed. A topical numbing cream may be applied to ensure your comfort throughout the process.
02
Application
Dr Shihan uses fine needles or a cannula to precisely administer the polynucleotides into the target layers of the skin.
03
Immediate Aftermath
You may experience mild swelling, redness, or small bumps at the injection sites, which typically resolve within 24–48 hours.
04
Results & Recovery
While some hydration is immediate, the cellular repair process takes time. Optimal results appear after a course of 3 treatments.
Is it right for me?
Polynucleotides are an excellent option for those looking to improve skin quality and address specific concerns without adding significant volume.
- Fine lines and wrinkles around the eyes or mouth
- Loss of skin elasticity and firmness
- Dull or dehydrated complexion
- Acne scarring or uneven skin texture
- Dark circles and hollows in the under-eye area
- Patients seeking natural, biological skin rejuvenation
Frequently Asked Questions
What is the downtime after polynucleotides?
You may experience small bumps at the injection sites, which typically resolve within 24 to 48 hours as the product is absorbed.
When will I see the results?
Results develop gradually as the skin regenerates. Most patients notice improvements in skin quality, hydration, and fine lines after 2 to 4 weeks, with optimal results seen after a full course.
How many sessions are recommended?
For best results, a course of 3-4 sessions spaced 3 to 4 weeks apart is usually recommended. Maintenance sessions every 6 months can help sustain the regenerative effects.
Is the treatment safe?
Yes, polynucleotides are highly purified natural DNA fragments that are fully biocompatible. They have a long history of safe use in restorative medicine and ophthalmology.
Let's create a treatment plan around you.
We provide clinical expertise in a calm environment to help you achieve natural, confidence-boosting results.
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